FIND THE UNFOUND ANTIGEN

Mother Nature is unpredictable

Artificial Intelligence (AI) methods are as best as what Mother Nature shares but not hides. We have the organic solution to find both AI hits and misses.

By bioengineering a fragment-able HLA protein in an Eppendorf tube, our HLA protein autonomously finds its MHC-I peptide and fragments if it does not.

We have created a simple yet artisanal solution to advance both (i) education and (ii) evidence-based medicine.

We enable smarter thinking and create a multi-pronged solution to target missed cancer antigens. Thus, minimising tumour antigen escape.

Unlimited Possibilities

A NEW EXPERIENCE

MHC-I peptide stability

More than just MHC-I peptide affinities, MHC-I peptide stability is a better indicator of immunogenicity.

Unusual MHC-I peptide lengths

Beyond 8 to 11-mer peptides, shorter and longer MHC-I peptides have been found. Use it to redesign extended peptide cassettes and mRNAs.

Standard MHC-I peptide lengths

Design peptide libraries from 8 to 11-mers. Be surprised when poorly predicted peptides are still MHC-I peptides. Use it to select the best stabilising MHC-I peptides as vaccines.

Post-modified peptides

We provide a fast approach to screen for MHC-I peptides that may be glycosylated or phosphorylated like their parent glycoproteins.

About HLA SG

We are devoted to redefine HLA biology. To find high-affinity and natural antigen-specific T cells across human diseases.

By creating a simple solution performed in a tube, we bring teaching topics such as antigen presentation into practical classes.

By discovering more T cell antigens, we develop multi-pronged solutions to deliver a more efficacious patient's experience.

It is time to find what Mother Nature hides and redefine the treatment of cancer.

Have any questions?

If you have any questions about the ONE MHC-I Discovery System, feel free to contact us.

Coming Soon

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Coming Soon

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Happy clients

TESTIMONIALS